Pharmocotherapy Principles and Practice-Solid-Organ Transplantation

Contact Hours: 2.5

ACPE No: 014-999-07-067-H04

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Learning Objectives

Upon completion of this activity the participant should be able to:
on completion of the chapter, the reader will be able to
1. Describe common reasons for the various solid-organ transplants.
2. Differentiate between the functions of cell-mediated and humoral immunity and how they relate to organ transplantation.
3. Describe the roles of the antigen-presenting cells in initiating the immune response.
4. Compare and contrast the types of rejection, including hyperacute, acute, chronic, and humoral.
5. Define the terms host-graft adaptation and tolerance, paying close attention to their differences.
6. Discuss the desired therapeutic outcomes and appropriate pharmacotherapy used to avoid allograft rejection.
7. Compare and contrast the currently available immunosuppressive agents in terms of mechanisms of action, adverse events, and drug-drug interactions.
8. Design an appropriate therapeutic regimen for the management of immunosuppressive drug complications based on patient-specific information.
9. Develop a therapeutic drug-monitoring plan to assess both the effectiveness and the adverse events of immunosuppressive drugs.

Faculty:

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MAC

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